Thalamic mediodorsal nucleus and its participation in spatial working memory processes: comparison with the prefrontal cortex
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چکیده
منابع مشابه
Thalamic mediodorsal nucleus and its participation in spatial working memory processes: comparison with the prefrontal cortex
Working memory is a dynamic neural system that includes processes for temporarily maintaining and processing information. Working memory plays a significant role in a variety of cognitive functions, such as thinking, reasoning, decision-making, and language comprehension. Although the prefrontal cortex (PFC) is known to play an important role in working memory, several lines of evidence indicat...
متن کاملThalamic mediodorsal nucleus and working memory.
Working memory is a dynamic neural system for temporarily maintaining and processing information. The prefrontal cortex (PFC) plays an important role in working memory. However, several evidences indicate that the thalamic mediodorsal nucleus (MD) also participates in working memory. Neurophysiological studies revealed that MD neurons exhibit sustained delay activity, which is considered to be ...
متن کاملThe prefrontal cortex: Projection area of the thalamic mediodorsal nucleus?
The historical bases of the definitions of the prefrontal cortex are reviewed (cytoarchitecture, electrical unexcitability, afferents from the mediodorsal thalamic nucleus). Evidence is presented that the widely accepted proposal of Rose and Woolsey (1948) to name all cortex prefrontal that is reached by afferents from the mediodorsal nucleus is questionable for three reasons: the diversity of ...
متن کاملRole of the thalamic nucleus reuniens in mediating interactions between the hippocampus and medial prefrontal cortex during spatial working memory
Despite decades of research, the neural mechanisms of spatial working memory remain poorly understood. Although the dorsal hippocampus is known to be critical for memory-guided behavior, experimental evidence suggests that spatial working memory depends not only on the hippocampus itself, but also on the circuit comprised of the hippocampus and the medial prefrontal cortex (mPFC). Disruption of...
متن کاملCortical projections of the thalamic mediodorsal nucleus in the rat. Definition of the prefrontal cortex.
Deposits of somatopetal tracers, that filled the entire dorsolateral cortex of one hemisphere, labelled only a few cell bodies in the thalamic mediodorsal nucleus (MD). Further experiments served to confirm the existence of strong projections from MD to the mesial and suprarhinal areas of the frontal cortex. Thus, only a very small proportion of the MD neurones in the rat projects outside the c...
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ژورنال
عنوان ژورنال: Frontiers in Systems Neuroscience
سال: 2013
ISSN: 1662-5137
DOI: 10.3389/fnsys.2013.00036